Crystal Engineering Studies: polymorphs and co-crystals
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چکیده
We review the key topics of one of the areas with the biggest impact of the last years in the chemical and pharmaceutical industry that is Crystal Engineering. The relevance of polymorphs and co-crystals from different points of view is been highlighted and broadly illustrated by means of several recent examples of studies carried out in this field. In addition, the most suitable instrumental techniques and the intellectual property implications are reviewed. Handbook of instrumental techniques from CCiTUB Crystal Engineering Studies 1 ChT.1
منابع مشابه
polymorphs, solvates and co-crystals. Functional groups that are self-complementary are capable of forming either a supramolecular homosynthons (eg-acid-acid and amide-amide homodimers or a supramolecular heterosynthon (carboxylicacid-amide heterodimers)
The emerging role of supramolecular chemistry and crystal engineering in pharmaceutical science has been influenced significantly by the interest in pharmaceutical cocrystals. Pharmaceutical co-crystals are co-crystals that are formed between an API (active pharmaceutical ingredient) and a co-crystal former that is a solid under ambient conditions. APIs contain functional groups that engage in ...
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تاریخ انتشار 2012